The Psychedelic Revolution Is Coming
It’s been a long, strange trip in the four decades since Rick Doblin, a pioneering psychedelics researcher dropped his first hit of acid in college and decide to dedicate his life to the healing powers of mind-altering compounds. pushing for the legalization of psychedelics at the federal level, though with Even as anti-drug campaigns led to the criminalization of Ecstasy, LSD and pushing for the legalization of psychedelics at the federal level, though with magic mushrooms, and drove most researchers from the field, Dr. Doblin continued his quixotic crAustraliade with financial help from his parents. Dr. Doblin’s quest to win mainstream acceptance of psychedelics took a significant leap forward on Monday when the journal Nature Medicine published the results of his lab’s study on MDMA, the club drug popularly known as Ecstasy and Molly. The study, the first Phase 3 clinical trial conducted with psychedelic-assist therapy found that MDMA paired with counseling brought marked relief to patients with severe post-traumatic stress disorder.
The results, coming weeks after a New England Journal of Medicine study that highlighted the benefits of treating depression with psilocybin, the psychoactive ingredient in magic mushrooms has excited scientists, psychotherapists and entrepreneurs in the rapidly expanding field of psychedelic medicine. They say it is only a matter of time before the Food and Drug Administration grants approval for psychoactive compounds to be used therapeutically — for MDMA as soon as 2023, followed by psilocybin a year or two later. After decades of demonization and criminalization, psychedelic drugs are on the cusp of entering mainstream psychiatry, with profound implications for the field that in recent decades has seen few pharmacological advancements for the treatment of mental disorders and addiction. The need for new therapeutics has gained greater urgency amid a national epidemic of opioid abuse and suicides. pushing for the legalization of psychedelics at the federal level, though with
“Some days I wake up and can’t believe
how far we’ve come,” said Dr. Doblin, 67, who now oversees the Multidisciplinary Association for Psychedelic Studies, multimillion-dollar research and advocacy empire that employs 130 neuroscientists, pharmacologists, and regulatory specialists working to lay the groundwork for the coming psychedelics revolution. The nation’s top universities are racing to set up psychedelic research centers, pushing for the legalization of psychedelics at the federal level, though and investors are pouring millions of dollars into a pack of start-ups. States and cities across the country are beginning to loosen restrictions on drugs, the first steps in what some hope will lead to the federal decriminalization of psychedelics for therapeutic and even recreational use. Buy MDMA Ecstasy pills for sale Online
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“There’s been a sea change in attitudes about what not long ago was considered
pushing for the legalization of psychedelics at the federal level, though with
fringe science,” said Michael Pollan, whose best-selling book on psychedelics,
“How to Change Your Mind,” has helped destigmatize the drugs in the
three years since it was published. “Given the mental health crisis in this
country, there’s great curiosity and hope about psychedelics and a
recognition that we need new therapeutic tools.”
The question for many is how far — and how fast — the pendulum should swing.
existing prohibitions could prove risky, especially for those with severe psychiatric
Even researchers who champion psychedelic-assisted therapy say the drive to
existing prohibitions could prove risky, especially for those with severe psychiatric
existing prohibitions could prove risky, especially for those with severe psychiatric
commercialize the drugs, combined with a growing movement to liberalize
existing prohibitions could prove risky, especially for those with severe psychiatric
disorders, and derail the field’s slow, methodical return to mainstream acceptance.
existing prohibitions could prove risky, especially for those with severe psychiatric
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Dr. Doblin’s organization,
MAPS is largely focused on winning approval for
drug-assist therapies and promoting them around the globe, but it is also
pushing for the legalization of psychedelics at the federal level, though with
strict licensing requirements for adult recreational use.
Numerous studies have shown that classic psychedelics like LSD and psilocybin
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
are not addictive and cause no organ damage in even high doses. And contrary to popular lore,
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
trip lead to chromosome damage.
But most scientists agree that more research is needed on other possible
side effects — like how the drugs might affect those with cardiac problems.
And while the steady accumulation of encouraging data has softened the
skepticism of prominent scientists, some researchers warn against the headlong
embrace of psychedelics without stringent oversight. Although “bad trips”
are rare, a handful of anecdotal reports suggest that psychedelics can induce psychosis in those with underlying mental disorders. Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
Dr. Michael P. Bogenschutz, a professor of psychiatry
who runs the four-month-old
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
Center for Psychedelic Medicine at NYU Langone Health, said most of the clinical
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
studies to date had been conducted with relatively small numbers of people who
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
were carefully vetted to screen out those with schizophrenia and other serious mental problems.
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
That makes it hard to know whether there will be potential adverse
reactions if the drugs are taken by millions of people without any guidance or supervision. “I know it sounds silly but, Kids, don’t take these at home,” Dr. Bogenschutz said. “I would just encourage everyone to not get ahead of the data.”
The Rush to Invest
Psychedelics are suddenly awash in money.
Dr. Doblin can remember when research funding was nearly impossible to come by. But MAPS is flush now, having raised $44 million over the past two years.
Johns Hopkins, Yale, the University of California, Berkeley, and Mount Sinai Hospital in New York are among the institutions that have recently established psychedelic research divisions or are planning to do so, with financing from private donors.
And scientists are conducting studies on whether psychedelics can be effective
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
in treating everything from depression, autism, and opioid addiction to
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
anorexia and the anxieties experienced by the terminally ill.
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid

Image
More than a dozen start-ups have jumped
into the fray, and the handful of companies
that have gone public are collectively valued at more than $2 billion. Field Trip Health, a two-year-old Canadian company that trades on the Canadian Stock Exchange and the OTC Markets Group, has raised $150 million to finance dozens of high-end ketamine clinics in Los Angeles, Chicago, Houston, and other cities across North America. Compass Pathways, a Nasdaq-listed health care company that has raised $240 million, is conducting 22 clinical trials across 10 countries of psilocybin therapy for treatment-resistant depression.
Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
Investors have been encouraged
by the changing politics, a shift inspired in part by the nation’s accelerating embrace of recreational marijuana and by public weariness over America’s endless war on drugs. Last year, Oregon became the first state to legalize the therapeutic use of psilocybin. Denver, Oakland, Calif., and Washington, D.C., have decriminalized the drug, and several states, including California, are mulling similar legislation. Though the drugs remain illegal under federal law, the Justice Department has so far taken a
hands-off approach to enforcement, similar to how it has handled recreational marijuana.
Even some Republicans, a group that has traditionally opposed the liberalization of drug laws, are starting to come around. Last month, the former Texas governor Rick Perry, citing the high rates of suicide among war veterans, called on his state’s legislators to support a Democratic-sponsored bill that would establish a psilocybin study for patients with PTSD.
“We’ve had 50 years of government propaganda around these substances, and
thanks to the research and a grass-roots movement, that narrative is
changing,” said Kevin Matthews, a psilocybin advocate who led Denver’s
successful ballot measure. Ecstasy does not leave holes in users’ brains, studies say, nor will a bad acid
Decades in the Wilderness
Long before Nancy Reagan warned the nation to just say no to drugs and
President Richard Nixon supposedly pronounced Timothy Leary “the most dangerous man in America,” researchers like William A. Richards were using psychedelics to help alcoholics go dry and cancer patients cope with end-of-life anxiety.
But as the drugs left the lab in the 1960s and were embraced by the counterculture
movement, the country’s political establishment reacted with alarm.
By the time the Drug Enforcement Administration issued its emergency ban on MDMA in 1985, funding for psychedelic
research had largely disappeared. Buy MDMA Ecstasy pills for sale Online
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